Keywords: T cell development and function; immune aging; systemic inflammation; signal transduction; gene expression.
Research in our laboratory focuses on the study of immunity, autoimmunity and inflammation. In particular, we are interested in understanding the role of peripheral, brain associated and gut-associated immune cells, as well as the gut-microbiota in the development of age-related chronic systemic inflammation and age-related neurological ailments including EAE, Parkinson’s and Alzheimer’s disease.
Ongoing projects include:
1. Study of transcription factors that regulate the development, maintenance and aging of conventional and innate immune cells.
2. Study of innate and adaptive immune cells in chronic neurological diseases, including EAE, Parkinson’s and Alzheimer’s disease.
3. Age-associated systemic inflammation and its role in chronic neurological diseases.
Profile: Publications and Interests