Keywords: Stem Cell models for human blood/immune development and diseases
Dr. Linzhao Cheng is a founding member of Stem Cell Program in the Johns Hopkins Institute for Cell Engineering (ICE). He is also a faculty member of the Graduate Training Programs in Cellular and Molecular Medicine and Immunology.
After receiving a PhD degree in Molecular Biology and Genetics from Hopkins in 1991, Dr. Cheng has been working on stem cell research in NIH, the biotech industry and academia. He has extensive experience in several types of stem cells including human hematopoietic stem cells (HSC), mesenchymal stem cells/marrow stromal cells (MSC), embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. In 2003 and nominated by NIH, Dr. Cheng received the Presidential Early Career Award for Scientists and Engineers, "for outstanding accomplishments in the field of stem cell research including pioneering research that is advancing our knowledge of human embryonic stem cell self-renewal and differentiation of blood cells". This Presidential Award is the highest honor bestowed by the U.S. government on outstanding scientists and engineers beginning their independent careers.
Dr. Cheng’s ICE laboratory is working on human stem cell biology and engineering, and their applications in cell and gene therapies as globally regenerative medicine. One of objectives is to understand developmental control of human immune as well as blood cells. His group currently focuses on using human pluripotent stem such as iPS cells from healthy donor and patients, including those with targeted or corrected mutations, to investigate human stem cell biology and diseases. See his publications since he joined ICE in 2003, or visit his lab website: www.stemcelllab.org.
Profile: Publications and Interests