Marsha Wills-Karp, Ph.D.
Ph.D. University of California Santa Barbara
Chairman, Department of Environmental Health Sciences
The Johns Hopkins Bloomberg School of Public Health
615 N. Wolfe St., Room E7527
Baltimore, Md. 21205
Office: (443) 287-4290
Fax: (410) 955-0617
Key words: Allergy, Asthma, Immunology, Genetics of Asthma, Microbiome
My research activities focus on defining the environmental and genetic determinants of allergic airway diseases such as asthma. My lab members and I have specifically explored the role of CD4+ Th2 cells and cytokines (IL-13), and innate immune pathways (complement activation pathways, TLRs, CLRs), in the pathogenesis of asthma. I have made substantial contributions to our understanding of the molecular mechanisms underlying allergenicity of common allergens-specifically how allergens and airborne pollutants activate innate immune pathways through molecular mimicry. More recently, I have turned my attention to how the gut microbiome alters susceptibility to allergen and PM-induced asthma.
Profile: Publications and Interests